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A Microscale Molecular Weight Analysis Method for Characterizing Polymers Solutions of Unknown Concentrations

Melissa Li

出版	Georgia Institute of Technology, 2008
URL	http://books.google.com.hk/books?id=kWl3AQAACAAJ&hl=&source=gbs_api

註釋

Molecular weight and concentration are two most important characteristics of polymers synthesized through chemical or microbial processes. However, current methods for characterizing polymer molecular weight such as Multi-Angle Laser Light Scattering (MALLS) or Gel Permeation Chromatography (GPC) require precise information on concentration as well as extensive sample preparation. Additionally, these current methods are also generally expensive, low throughput, and require large sample titers. These limitations prevent dynamic time-point studies of changes in molecular weight, which would be very useful for monitoring synthesis progress in microbes or in chemical synthesis.