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THE REGULATION OF GROWTH HORMONE BINDING SITES IN RAT LIVER MEMBRANES.
註釋controls. In contrast, the i.v. administration of bGH (200 ug) to hypophysectomized rats 5-60 min before they were killed almost eliminated specific binding of bGH to the isolated membranes. This decrease may be due to the development of a nondissociable hormone-binding site complex which reduces the number of available binding sites. The changes in bGH binding to the rat liver membranes produced by GH deficiency or acute GH administration appear to correlate with known changes in the sensitivity of the