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Some Thyrotropic Agents

IARC Working Group on the Evaluation of Carcinogenic Risks to HumansInternational Agency for Research on Cancer

出版	World Health Organization, 2001
主題	Health & Fitness / Diseases & Conditions / CancerMedical / Health Risk AssessmentMedical / Oncology / GeneralMedical / Public HealthMedical / ToxicologyTechnology & Engineering / Food Science / GeneralTechnology & Engineering / Food Science / Chemistry & Biotechnology
ISBN	92832127979789283212799
URL	http://books.google.com.hk/books?id=l965aqw_LSkC&hl=&source=gbs_api
EBook	SAMPLE

註釋

This volume evaluates carcinogenicity to humans of 19 chemicals that are carcinogenic to the thyroid follicular-cell epithelium in rodents. These included some so-called "anti-thyroid" drugs (methimazole, methylthiouracil, propylthiou-racil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole. Other chemicals are or have been used in agriculture as pesticides (amitrole, chlordane/heptachlor, hexachlo-robenzene and toxaphene), in foods and cosmetics (kojic acid), in hair dyes (2 4-diaminoanisole) or as industrial chemicals (N N'-diethylthiourea, ethylenethiourea and thiourea).