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Prognostic Value of the CLIF‐C AD Score in Patients with Implantation of Transjugular Intrahepatic Portosystemic Shunt
Lukas Sturm
Michael Praktiknjo
Dominik Bettinger
Jan Patrick Huber
Lara Volkwein
Arthur Schmidt
Rafael Simon Peter Käser
Johannes Chang
Christian Jansen
Carsten Meyer
Daniel K. Thomas
Robert Thimme
Jonel Trebicka
Michael Schultheiß
出版
Universität
, 2021
URL
http://books.google.com.hk/books?id=liiDzgEACAAJ&hl=&source=gbs_api
註釋
Abstract: Prognostic assessment of patients with liver cirrhosis allocated for implantation of a transjugular intrahepatic portosystemic shunt (TIPS) is a challenging task in clinical practice. The aim of our study was to assess the prognostic value of the CLIF-C AD (Acute Decompensation) score in patients with TIPS implantation. Transplant-free survival (TFS) and 3-month mortality were reviewed in 880 patients who received de novo TIPS implantation for the treatment of cirrhotic portal hypertension. The prognostic value of the CLIF-C AD score was compared with the Model for End-Stage Liver Disease (MELD) score, Child-Pugh score, and albumin-bilirubin (ALBI) score using Harrell's C concordance index. The median TFS after TIPS implantation was 40.0 (34.6-45.4) months. The CLIF-C AD score (c = 0.635 [0.609-0.661]) was superior in the prediction of TFS in comparison to MELD score (c = 0.597 [0.570-0.623], P = 0.006), Child-Pugh score (c = 0.579 [0.552-0.606], P 0.001), and ALBI score (c = 0.573 [0.545-0.600], P