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High Resolution Radionuclide Imaging Using Focusing Gamma-Ray Optics
C. Taylor
W. Craig
K. Ziock
M. Pivovaroff
B. Hasegawa
W. Barber
T. Funk
出版
United States. Department of Energy
, 2004
URL
http://books.google.com.hk/books?id=m3gJkAEACAAJ&hl=&source=gbs_api
註釋
Significant effort is being devoted to the development of noninvasive imaging systems that allow in vivo assessment of biological and biomolecular interactions in mice and other small animals. Although single-photon emission tomography (SPECT) and positron emission tomography (PET) are well-matched to the study of physiological function in small animals, the spatial resolutions of 1-2 mm currently achievable with these techniques limits the types of research possible. For this reason, we are developing a small animal radionuclide imaging system using grazing incidence optics to focus the low-energy gamma-rays emitted by {sup 125}I, {sup 95m}Tc, {sup 96}Tc, and {sup 99m}Tc. We compare this approach to the more traditional use of absorptive collimation.
