The Brownsville Agreement and the Mérida Initiative were collaborative inter-agency agreements between the United States and Mexico. The War on Drugs has taken thousands of lives on both sides of the border and these agreements provided a collaborative framework to influence the outcome of the war. Using Outcomes Theory and Time Series/Intervention Analysis, multiple outcomes demonstrated that consequences from these policies were an overwhelming loss for the War on Drugs. After these policies were implemented, drug use in the US rose, overall arrests remained static and street-prices of these illicit substances fell.