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註釋This volume critically and objectively analyses the literature up to 1989 and presents a guide to the practical use of all calcium antagonists which have been thoroughly investigated to date. It begins with a concise review of physiological principles as a basis for a discussion of the general and specific pharmacodynamics and pharmacokinetics of calcium antagonists. Special emphasis is given to their therapeutic use in practice, precise dosage schedules are provided, interactions with other medications described, and therapeutic alternatives considered.