This book is the product of the authors’ research and clinical practice in the field of psycho-oncology, stress, and coping for a period of over twenty years. It fills a gap that exists in the discussion of caregiver distress felt by both cancer researchers and psycho-oncologists in the vital area of predicting, acknowledging, and alleviating the distress of caregivers of cancer patients, and it focuses on the caregivers of cancer patients in various phases of the illness. The discussion of cancer-patient caregivers is divided into three aspects: theoretical (Part 1), research (Part 2), and practical (Part 3) issues. The analysis of these areas can be useful to clinicians, researchers, medical/psychological social workers, and nurses by familiarizing them with the spectrum of stresses experienced by cancer patients and their caregivers, and the coping methods that have proven most effective. Part One presents theoretical background on the structure and progression of the caregiver role and how caregivers cope with the illness as explored in recent literature. Part Two presents empirical research on caregiver psychological distress carried out by the authors during 1993-1999. Part Three examines two important issues. The first is intervention for reducing caregiver distress, and the second issue is the ethical question of caregiver involvement in the patient’s medical decisions. The book is timely, as it is felt that the issue at hand will have mounting importance and relevance to our society as it experiences growing longevity and concomitant challenges in cancer caregiving.