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Radiation Effects in Man: Manifestations and Therapeutic Efforts

出版	Defense Technical Information Center, 1970
URL	http://books.google.com.hk/books?id=oPpjNwAACAAJ&hl=&source=gbs_api

註釋Section 1 of this report presents the results of whole- and partial-body radiation given to 85 adults with far advanced cancer and three children with Ewing's sarcoma between 19 February 1960 through 31 August 1971. These studies fall into Phase I (is the treatment toxic) and Phase II (is the treatment effective but with no controls). In patients with carcinoma of the colon metastic to liver, survival after one to two treatments was about equivalent to that achieved with 5-fluorouracil therapy. In patients with bronchogenic cancer with metastases there was significant improvement in survival cancer, survival was better than that of patients treated solely with estrogens and androgens but was not quite as good as in a group treated with 5 FU. Three children receiving prophylactic radiation for Ewing's tumor are living although there has been a pulmonary recurrence in one child. No significant difference in time to death could be found when comparing treated and untreated patients in this series. Reactions from treatment were no more severe and in general less than those encountered with chemotherapy. Section 2 discusses an evaluation of thermography in determining skin changes and as an index of dose levels to skin. (Modified author abstract).