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Resolving Misalignment Limitations of Wireless and Batteryless Brain Implants

出版	Ohio State University, 2021
URL	http://books.google.com.hk/books?id=pBs0zwEACAAJ&hl=&source=gbs_api

註釋Neuro-sensing of the human brain has unparallel benefits when it comes to early detection of neural disorders like Alzheimer’s, Parkinson’s, multiple sclerosis, epilepsy, etc. However present neuro-sensing techniques suffers with various crisis. Some of them being immobility of patients due to use of intracranial wires, frequent surgeries for replacement of batteries and heating issues due to dense electronics. Passive neuro-sensing techniques have been reported to deal with these issues. However, shift from traditional to passive neuro-sensing system introduced complications like misalignment loss. State of the art neuro-sensing technologies suffered with losses of about 10 dB in case of misalignment in human brain in-vitro settings. This thesis presents a neuro-sensing antenna system that is able to read a complete range of neural signals keeping the misalignment losses less than 2 dB. A canonical four-layer human head and a three-layer rat head model is presented. The previous state of the art neuro-sensing antenna systems are simulated in these head models for misalignment losses. High simulation time was observed when these systems were tested in human and rat head model. To reduce the simulation time a canonical single layer human and rat head model was proposed. Up to 3 times reduction in simulation time was observed in single layer as opposed to multi-layer head models. A bump is also proposed in rat head model to accommodate the implant and help in realistic and error-free modelling. The proposed technique will also help in accurate mapping of the rat head models for in-vivo measurements. A new antenna system with an interrogator (antenna used to receive neural signals) and an implant antenna is proposed. The enhanced transmission coefficient and reduced misalignment losses help in efficiently increasing the sensitivity up to 20 μVpp. The amount of power transferred by the interrogator antenna towards the implant is reduced for the antenna pair to follow both the FCC and the ICNIRP standards.