登入選單
返回Google圖書搜尋
Animal Models for the Study of Human Disease
Matthew W. KempGabrielle C. MuskMasatoshi Saito
其他書名
Chapter 35. Animal Models for the Study of Infection-Associated Preterm Birth
出版Elsevier Inc. Chapters, 2013-05-29
主題Medical / GeneralScience / Life Sciences / Zoology / GeneralScience / Life Sciences / BiologyMedical / Laboratory MedicineScience / Life Sciences / GeneralScience / Life Sciences / Anatomy & PhysiologyMedical / Internal Medicine
ISBN01280722539780128072257
URLhttp://books.google.com.hk/books?id=pZxzDAAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋In industrialized and developing countries, preterm birth (live delivery before 39 weeks of gestation) is both a leading cause of neonatal death and a major risk factor for respiratory, neurological, and cognitive disabilities in those infants who survive to adolescence. Intrauterine infection is considered a leading cause of preterm birth; data from clinical and experimental studies suggest that in utero infection accounts for upward of 40% of preterm deliveries. This chapter is written with two aims: the first is to provide the reader with an introduction to infection-associated preterm birth, highlighting the importance of animal-based studies in the development of this field; and the second, adopting a practical focus, is designed to provide the reader with technical insight into the use of sheep as a model organism for the study of fetal inflammatory responses to the presence of microbial agonist in the uterine sphere.