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Hyperacute Xenograft Rejection
Jeffrey L. Platt
出版
Springer-Verlag
, 1995
主題
Medical / Immunology
Medical / Surgery / Cosmetic & Reconstructive
Medical / Surgery / Transplant
ISBN
3540588922
9783540588924
URL
http://books.google.com.hk/books?id=s_9qAAAAMAAJ&hl=&source=gbs_api
註釋
This book is about hyperacute xenograft rejection, a humoral immune reaction which destroys a vascularized organ graft within minutes to a few hours. The author summarizes classical concepts concerning the immunologic basis for hyperacute xenograft rejection including the role of natural antibodies and complement. Recent insights into the pathogenesis are considered, as are potential approaches to the prevention and treatment. The risk of hyperacute xenograft rejection has been considered an absolute contraindication to transplantation; the author discusses whether, in light of new developments, that view should be changed.