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INDUCIBLE REPAIR OF DNA DAMAGE FROM N-METHYL-N'-NITRO-N-NITROSOGUANIDINE OR BIS-(2-CHLOROETHYL)-SULFIDE (ALKALI-LABICE-LESIONS, ALKYLATION).

DAVID HOWARD SORSCHER

出版	University of MICHIGAN, 1986
URL	http://books.google.com.hk/books?id=tus9AAAAMAAJ&hl=&source=gbs_api

註釋

repair was observed in cultures pretreated with a low concentration of MNNG which did not cause measurable DNA damage. Inhibition of the DNA polymerization phase of the DNA repair process by treatment with aphidicolin (APC) during post-challenge incubation resulted in equivalent declines in DSDNA in pretreated and not-pretreated cultures and no return of DSDNA toward control levels and suggests that components of the DNA repair process which cause SSB (i.e., incision and excision) were not affected by