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Chapter 23. Wilms Tumors
出版Elsevier Inc. Chapters, 2013-11-21
主題Medical / GeneticsScience / Life Sciences / Genetics & GenomicsScience / Life Sciences / General
ISBN01280612009780128061206
URLhttp://books.google.com.hk/books?id=w1xzDAAAQBAJ&hl=&source=gbs_api
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註釋Wilms tumors are pediatric tumors of the kidney found in young children with a mean age of 40 months. Genes found mutated in Wilms tumors have essential functions in the early stages of nephron development. Different subsets of Wilms tumors can be recognized via genetic and transcriptomic analysis and ontological analysis of expression patterns suggests different developmental origins for different tumor classes. A better understanding of normal early kidney development will help the design of new therapeutic approaches for different classes of Wilms tumors.