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Google圖書搜尋
Psoralen Derivatives as Non-peptidic Inhibitors of Chymotrypsin-like Activity of the Immunoproteasome
Izidor Sosič
Martina Gobec
Boris Brus
Damijan Knez (farmacevt.)
Aleš Obreza
Irena Mlinarič-Raščan
Stanislav Gobec
其他書名
Patentna Prijava : Int. Publ. No. WO/2016/151483 A 1
出版
World Intellectual Property Organization, International Bureau
, 2016
URL
http://books.google.com.hk/books?id=wRejAQAACAAJ&hl=&source=gbs_api
註釋
This invention relates to new inhibitors of chymothrypsin-like activity of the immunoproteasome (inhibitors of %5% or LMP7 subunit) with the general formula (I), where substituents are described in patent description. Compounds can be in the form of pure enantiomers or as racemic mixtures, or in the form of pharmaceutically acceptable salts. The present invention relates to the use of these inhibitors for the treatment of diseases where immunoproteasome activity is increased.
