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Physical Methods for In-vivo Evaluation of Heavy and Other Toxicological Metals
註釋Physical methods, which include x-ray fluorescence (XRF) and fast neutron activation, are rapidly becoming established as powerful tools in the study of body composition. Particular foci of attention are the monitoring of heavy metal exposure, either in the living environment of occupationally, biological processes, organ dysfunction and the effiency of therapeutic regimes including chelation. The relative simplicity of the facilities which are required have allowed increasing interest to be shown in the development of portable in-vivo systems. This talk will attempt to review some of the important developments which have occurred. Efforts to enhance the ratio of measurent sensitivity to radiation dose will be highlighted. Examples will include monitoring of occupational Pb exposure and possibilities for the monitoring of iron overload which sometimes occurs in association with the treatment of thalassaemia. [Author's abstract].