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Bioinformatic Investigations in Marine Microbial Ecology
註釋Chapter 2: Marine cyanobacteria capable of fixing molecular nitrogen ("diazotrophs") are key in biogeochemical cycling; the nitrogen fixed is a major external source of nitrogen to the open ocean. Candidatus Atelocyanobacterium thalassa (UCYN-A) is a diazotrophic cyanobacterium known for its widespread geographic distribution, unusually reduced genome, and symbiosis with a single-celled prymnesiophyte alga. Recently a novel strain of this organism, called UCYN-A2, was detected in coastal waters off southern California. We assembled and analyzed the metagenome of this UCYN-A2 population. UCYN-A2 and the open-ocean UCYN-A1 strain share most protein-coding genes with high synteny, yet average amino-acid sequence identity between orthologous genes is only 86%. Our results suggest that UCYN-A1 and UCYN-A2 had a common ancestor and diverged after genome reduction