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Neuronal Activity Suppression of Kv1.1 ChannelmRNA Translation in Dendrites

出版	University of California, San Francisco, 2006
ISBN	05428291189780542829116
URL	http://books.google.com.hk/books?id=z-87bqQSa08C&hl=&source=gbs_api

註釋Ion channels play crucial roles in a variety of cellular activities. A superfamily of ion channels known as voltage-gated ion channels is responsive to changes in the electrical potential across the cell membrane in which they reside. This property of voltage sensitivity allows voltage-gated ion channels to be major contributors to the electrical communication utilized by cells. The prominence of these channels in many biological processes has made them a popular drug target in hopes of treating a variety of pathologies. Chapter I is a broad overview of these voltage-gated ion channels with a particular emphasis on the pharmacology developed and discovered for these channels.