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The Overpressure-duration Relationship and Lethality in Small Animals
Donald R. Richmond
V. C. Goldizen
Victor R. Clare
Clayton S. White
出版
Lovelace Foundation for Medical Education and Research
, 1962
URL
http://books.google.com.hk/books?id=drkUeyIj0ngC&hl=&source=gbs_api
EBook
FULL_PUBLIC_DOMAIN
註釋
A total of 993 mice, rats, guinea pigs and rabbits were exposed to sharp-rising overpressures of various short durations. They were mounted on a concrete pad above which high-explosive charges, ranging in weight from 0.50 oz to 64 lbs, were detonated. Pressure-time measurements were obtained with pencil-type and shock-tube piezo-electric gauges on the pad directly beneath the charges. The duration of the blast waves ranged from 0.40 msec to 6.8 msec. The LD-50 pressures were calculated for each species at the different pulse durations. In general, the pressures required to produce 50-percent lethality rose at the shorter durations. Combining the results of this study with those from previous shock-tube investigations made it possible to define the tolerance of four small-animal species to sharply rising overpressures as a function of pulse duration.
